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3D Reconstruction of histological slices

3D Reconstruction of histological slices

HistoDigital (HiD) is an application that enables you to create a digital 3D reconstruction of the anatomical tissue structures from the datasets of your histological slide images. In the spatial reconstruction of your data with HiD, we attach particular importance to the anatomically accurate reconstruction of the original tissues through the iterative application of special algorithms in order to enable a powerful analysis an interpretation of the structures. Thereby staining variances are corrected.

 

Benefit from the high resolution of light microscopy

High resolution

High level of detail due to light microscopy

Digital 3D reconstruction allows view from different angles.

3D Imaging

Digitally reconstructed tissue can be accessed from all sides

Accurate and fast reconstruction through innovative algorithms

Accurate reconstruction

We attach particular importance to the anatomically accurate reconstruction of the original tissues

Applications

Features

Possible Applications where Digital Radiology could be used for are:                                   

  • Access tissue from all sides
  • Exemption from anatomical structures (segmentation)
  • Visualize topographical situation
  • 3D tissue analysis
  • Digital Pathology
 		 
  • The user interface gives you quick and clear access to all functionalities of the program
  • Different display options for your image data
  • Ony a few mouse clicks to a successful and qualitatively unrivaled 3D reconstruction
 

 

3D reconstruction of histological slices of a kidney allowing views from different perspectives

Work Cases

Kidney

In this example a 3D reconstruction has been done on histological slides from a fetal kidney dataset.The right images show transversal and sagittal view of the 3D volumetric reconstructed kidney.

3D reconstruction of a paraffin embedded pig lacrimal gland (grey) along with a segmentation of seven excretory lacrimal ducts

Lacrimal gland

The image on the left shows the 3D reconstruction of a paraffin embedded pig lacrimal gland (grey) along with a segmentation of seven excretory lacrimal ducts (different colors).

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