The goal of image registration is to compensate for the patient motion between different image acquisitions, be it follow-up acquisitions, image stitching or acquisitions in different imaging modalities such as CT, MR or PET/SPECT.
Obtain more precise rigid registration compared to ordinary registration
Reduce turnaround time
In current clinical practice and healthcare centers
Increase diagnosis quality
Through good alignment of the images pathologies are easier to detect
The transformation between the images is limited to only rotations and translations. This method is used to establish a link between different scanner coordinate systems or to account for rigid body movements
Techniques allow far more degrees of freedom compared to rigid registration. It can be used to compute complex deformations between images, for example due to breathing motion and soft tissue deformations. Even inter-patient registration is possible in order to build atlases of various subjects
Compenstation of breathing motion in PET-CT image pair of melanoma patient. The images have been acquired at different times with single scanners. The example shows an exemplary slice from the 3-D volumes.